What is impermanence?

Impermanence is the fact that even when you are in good health, in good fortune, there is no guarantee that it will continue, and it is very distressing.
Death is only the most extreme form of impermanence.

To accept impermanence, Buddhism recommends giving up attachment. This specifies the complementary meaning to be given to our advice 'Domesticate pleasure' in terms of the question 'How to succeed in life?'.